Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158907 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL5054915 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL5054919 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL13744292 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL4195137 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL24365527 | 1.00 | SLC18A3 (0.39) | SLC18A3SIGMAR1CHRNB2CHRNA4MEN1 | |
| SCHEMBL2708040 | 0.81 | KDM1A (0.37) | PRCP | |
| SCHEMBL22473286 | 0.81 | KDM1A (0.37) | PRCP | |
| SCHEMBL2708049 | 0.81 | KDM1A (0.37) | PRCP | |
| SCHEMBL12980157 | 0.81 | KDM1A (0.37) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-08-06 | — | — | US | disclosed |
| EP-0305180-B1 | Enantioselective reduction of ketones | HARVARD COLLEGE (US) | 1995-03-22 | — | — | EP | disclosed |
| US-4943635-A | OXAZABOROLIDINES AND OXAZABORINES AS CATALYSTS | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 1990-07-24 | — | — | US | disclosed |
| EP-0305180-A2 | Enantioselective reduction of ketones | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-03-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090198052-A1 | METHOD FOR PREPARING OPTICALLY ACTIVE PIPERIDINE COMPOUNDS | SNCA, SYNJ1, KCNH2 | SLC18A3 547/4885SIGMAR1 651/4885CHRNB2 1699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.