SCHEMBL9158980

SCHEMBL9158980

CC1(C)CC(NCC(=O)NC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.56
HTT P42858 2/20 0.52
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.51
POLB P06746 3/20 0.48
RECQL P46063 2/20 0.48
MEN1 O00255 1/20 0.48
MAPT P10636 1/20 0.48
USP2 O75604 1/20 0.48
EZH2 Q15910 1/20 0.47
PKM P14618 1/20 0.46
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8771939 0.85 GAA (0.59) GAAHTTKMT2AKDM4EPOLB
SCHEMBL8335975 0.84 GAA (0.44) GAAHTTKMT2AKDM4EPOLB
SCHEMBL2901212 0.83 GAA (0.71) GAAHTTKMT2AKDM4EPOLB
SCHEMBL311701 0.83 GAA (0.61) GAAHTTKMT2AKDM4EPOLB
SCHEMBL9198978 0.81 EZH2 (0.45) GAAHTTKMT2AKDM4EPOLB
SCHEMBL10584545 0.80 EZH2 (0.44) GAAHTTKMT2AKDM4EPOLB
SCHEMBL29494819 0.80 GAA (0.58) GAAHTTKMT2AKDM4EPOLB
SCHEMBL9682135 0.80 GAA (0.58) GAAHTTKMT2AKDM4EPOLB
SCHEMBL1647940 0.80 GAA (0.67) GAAHTTKMT2AKDM4EPOLB
SCHEMBL28800695 0.80 GAA (0.58) GAAHTTKMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5449776-A Polypropylene CIBA-GEIGY CORPORATION (US) 1995-09-12 US disclosed
EP-0627428-A1 Piperidine-triazine compounds as light heat and oxidation stabilizers for organic materials CIBA-GEIGY AG (CH) 1994-12-07 EP disclosed