Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL3468577 | 0.94 | ALDH1A1 (0.86) | — | |
| Alcohol SCHEMBL1891803 | 0.94 | — | — | |
| Alcohol SCHEMBL3337506 | 0.94 | — | — | |
| Alcohol SCHEMBL11179267 | 0.94 | — | — | |
| Alcohol SCHEMBL19499 | 0.94 | — | — | |
| Alcohol SCHEMBL28999938 | 0.94 | — | — | |
| Alcohol SCHEMBL217195 | 0.94 | — | — | |
| Alcohol SCHEMBL1946699 | 0.94 | — | — | |
| Alcohol SCHEMBL2783941 | 0.88 | — | — | |
| Alcohol SCHEMBL11315136 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641328-A1 | BRIDGED AZA-BICYCLIC DERIVATIVES AS SUBSTANCE P ANTAGONISTS | PFIZER INC. (US) | 1995-03-08 | — | — | EP | disclosed |