Tetrachloroethylene

Tetrachloroethylene

SCHEMBL9159397

ClC(Cl)=C(Cl)Cl.ClCC(Cl)CCl.[CH]

nearest known ligand 0.50

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrachloroethylene SCHEMBL10611550 0.96 TSHR (0.53) TSHRTP53TDP1ALDH1A1
1,2,3-Trichloropropane SCHEMBL9165802 0.84
1,2,3-Trichloropropane SCHEMBL19623 0.80
Tetrachloroethylene SCHEMBL9734827 0.77 TSHR (0.42) TSHRTP53TDP1ALDH1A1
1,2,3-Trichloropropane SCHEMBL5060026 0.76
1,2,3-Trichloropropane SCHEMBL9420254 0.76
1,2,3-Trichloropropane SCHEMBL28332200 0.76
1,2,3-Trichloropropane SCHEMBL10413199 0.74 TSHR (0.53) TSHRTP53TDP1ALDH1A1
1,2,3-Trichloropropane SCHEMBL10419813 0.73 TSHR (0.50) TSHRTP53TDP1
1,2,3-Trichloropropane SCHEMBL6690126 0.71 TSHR (0.93) TSHRTP53TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5380772-A Modelling liquid for dental porcelain G-C TOSHI KOGYO CORPORATION (JP) 1995-01-10 US disclosed