Tetrachloroethylene

Tetrachloroethylene

SCHEMBL9734827

ClC(Cl)=C(Cl)Cl.ClCC(Cl)Cl

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.35
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16435 0.82
SCHEMBL28154792 0.82 TSHR (0.40) TSHRTP53TDP1ALDH1A1
Tetrachloroethylene SCHEMBL10611550 0.80 TSHR (0.53) TSHRTP53TDP1ALDH1A1
Methyl Alcohol SCHEMBL1871619 0.78
SCHEMBL4834201 0.77
Tetrachloroethylene SCHEMBL9159397 0.77 TSHR (0.50) TSHRTP53TDP1ALDH1A1
Water SCHEMBL6706113 0.77
Ammonia Solution, Strong SCHEMBL6917054 0.77
Hydrochloric Acid SCHEMBL11437100 0.77
SCHEMBL11822312 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5114986-A Halohydrocarbon blowing agent THE DOW CHEMICAL COMPANY (US) 1992-05-19 US disclosed
US-4996242-A Polyurethane foams manufactured with mixed gas/liquid blowing agents THE DOW CHEMICAL COMPANY (US) 1991-02-26 US disclosed