Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001989 | 1.00 | CNR2 (0.42) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL27865091 | 0.84 | CNR2 (0.40) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL27512117 | 0.81 | PPARA (0.41) | MEN1KMT2APPARAOPRM1 | |
| SCHEMBL17724548 | 0.81 | ALDH1A1 (0.51) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL5037418 | 0.81 | ALDH1A1 (0.51) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL6388938 | 0.80 | CNR2 (0.39) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL9283883 | 0.80 | CNR2 (0.46) | CNR2KMT2ACYP3A4PPARGPPARA | |
| SCHEMBL29974418 | 0.78 | MEN1 (0.57) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL9446766 | 0.78 | MEN1 (0.57) | CNR2MEN1KMT2ACYP3A4CES2 | |
| SCHEMBL27771442 | 0.78 | HPGD (0.44) | MEN1KMT2APPARGPPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430060-A | Aldose reductase inhibitor | ZENECA LIMITED (GB) | 1995-07-04 | — | — | US | disclosed |
| US-5270342-A | Acetamide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-14 | — | — | US | disclosed |
| EP-0469887-A1 | Acetamide derivatives | ZENECA LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |