Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | GGT1 | P19440 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 6/20 | 0.48 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9246910 | 0.86 | KDM4E (0.54) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9159803 | 0.84 | RARA (0.49) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL9159796 | 0.84 | RARA (0.49) | KDM4ELMNAALDH1A1BLMTDP1 | |
| SCHEMBL9127200 | 0.84 | RARA (0.57) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL8394232 | 0.84 | KDM4E (0.52) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL8690755 | 0.81 | KDM4E (0.43) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL8691421 | 0.81 | KDM4E (0.41) | KDM4EHSD17B10LMNACYP1A2CYP2C9 | |
| SCHEMBL9134128 | 0.81 | RARA (0.63) | KDM4EHSD17B10LMNAALDH1A1HPGD | |
| SCHEMBL9284517 | 0.79 | MAPT (0.43) | LMNACYP2C9ALDH1A1HPGDBLM | |
| SCHEMBL8461975 | 0.78 | RARA (0.61) | KDM4ELMNAALDH1A1HPGDBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409728-B1 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CIRD GALDERMA (FR) | 1995-03-01 | — | — | EP | disclosed |
| EP-0409728-A2 | Bi-aromatic esters, process for their preparation and their use in human or animal medicine and in cosmetics | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | disclosed |