Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462495 | 0.96 | MAPT (0.63) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10459733 | 0.95 | MAPT (0.66) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10462420 | 0.95 | MAPT (0.57) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10461702 | 0.94 | MAPT (0.64) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10461182 | 0.94 | MAPT (0.64) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10462751 | 0.94 | MAPT (0.64) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10461361 | 0.94 | MAPT (0.64) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10462239 | 0.94 | MAPT (0.64) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10462727 | 0.92 | MCHR1 (0.51) | L3MBTL1MAPTRAB9ACASP3SENP8 | |
| SCHEMBL10461061 | 0.92 | RAB9A (0.69) | L3MBTL1MAPTRAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0473208-B1 | Liquid crystal compounds containing a pyrazine or pyridine ring | MERCK PATENT GMBH (DE) | 1995-03-15 | — | — | EP | disclosed |
| EP-0473208-A2 | Liquid crystal compounds containing a pyrazine or pyridine ring | MERCK PATENT GmbH (DE) | 1992-03-04 | — | — | EP | disclosed |
| US-4913837-A | Heterocyclic compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-03 | — | — | US | disclosed |
| WO-1987004158-A2 | HETEROCYCLIC COMPOUNDS AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-07-16 | — | — | WO | disclosed |