SCHEMBL9160032

SCHEMBL9160032

O=C(NCCOc1ccc(Oc2cc(F)cc(F)c2)cc1Cl)OC(CF)CF

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 15/20 0.44
PPARD Q03181 11/20 0.44
PPARG P37231 5/20 0.43
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
ALDH1A1 P00352 1/20 0.38
MEN1 O00255 1/20 0.38
PKM P14618 1/20 0.38
KMT2A Q03164 1/20 0.38
HPGD P15428 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9302626 0.88 PPARA (0.49) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9163216 0.87 PPARA (0.41) PPARAPPARDPPARGMEN1PKM
SCHEMBL9163366 0.87 PPARA (0.45) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9160091 0.86 PPARA (0.49) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9157637 0.86 PPARA (0.47) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9157535 0.86 PPARA (0.47) PPARAPPARDPPARGHPGD
SCHEMBL9280073 0.85 PPARA (0.46) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9157443 0.85 PPARA (0.46) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9163413 0.85 PPARA (0.46) PPARAPPARDPPARGNPC1RAB9A
SCHEMBL9162070 0.83 PPARA (0.51) PPARAPPARDPPARGNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460472-B1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5346920-A Insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-09-13 US disclosed
EP-0460472-A1 Carbamic acid derivatives, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-12-11 EP disclosed