Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11263631 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11263628 | 0.87 | ALDH1A1 (0.36) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11428334 | 0.86 | ALDH1A1 (0.45) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL16078925 | 0.82 | ALDH1A1 (0.34) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL14453509 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL15827401 | 0.80 | ALDH1A1 (0.32) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL15000603 | 0.78 | ALDH1A1 (0.40) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL11671065 | 0.77 | — | — | |
| SCHEMBL20851115 | 0.77 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 | |
| SCHEMBL15831675 | 0.77 | TSHR (0.39) | ALDH1A1TDP1TSHRMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421379-B1 | Preparation of monoepoxides | DOW CHEMICAL CO (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0421379-A1 | Preparation of monoepoxides | THE DOW CHEMICAL COMPANY (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4341658-A | CATIONIC, AND ANIONIC POLYMER CATALYSTS | THE DOW CHEMICAL CO. (US) | 1982-07-27 | — | — | US | disclosed |
| US-4276406-A | COMPRISING A SUBSTRATE WITH ION EXCHANGEABLE CATIONS REACTED WITH A CATIONIC POLYMER | THE DOW CHEMICAL COMPANY (US) | 1981-06-30 | — | — | US | disclosed |