SCHEMBL916048

SCHEMBL916048

O=P(Cc1ccc(Cl)cc1)(Oc1ccccc1)Oc1ccccc1.[NaH]

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KLK8 O60259 2/20 0.57
PLAU P00749 2/20 0.57
KLK2 P20151 2/20 0.57
KLK4 Q9Y5K2 2/20 0.57
HPGD P15428 2/20 0.46
L3MBTL1 Q9Y468 4/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
TP53 P04637 2/20 0.45
GAA P10253 2/20 0.45
SRC P12931 1/20 0.41
HTT P42858 3/20 0.41
ALDH1A1 P00352 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
LMNA P02545 1/20 0.40
PPARG P37231 3/20 0.39
PPARA Q07869 3/20 0.39
NR4A2 P43354 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL916422 0.98 KLK8 (0.59) KLK8PLAUKLK2KLK4HPGD
SCHEMBL20703788 0.86 KLK8 (0.48) KLK8PLAUKLK2KLK4HPGD
SCHEMBL563232 0.85 KLK8 (0.63) KLK8PLAUKLK2KLK4HPGD
SCHEMBL916423 0.81 SRC (0.48) KLK8PLAUKLK2KLK4HPGD
SCHEMBL29267239 0.81 KLK8 (0.59) KLK8PLAUKLK2KLK4HPGD
SCHEMBL4231397 0.81 KLK8 (0.59) KLK8PLAUKLK2KLK4HPGD
SCHEMBL29113251 0.81 TP53 (0.51) KLK8PLAUKLK2KLK4HPGD
SCHEMBL916046 0.80 MEN1 (0.47) KLK8PLAUKLK2KLK4HPGD
SCHEMBL28701098 0.79 KLK8 (0.57) KLK8PLAUKLK2KLK4HPGD
SCHEMBL6766317 0.77 KLK8 (0.55) KLK8PLAUKLK2KLK4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed