Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK8 | O60259 | 2/20 | 0.59 |
| ▸ | PLAU | P00749 | 2/20 | 0.59 |
| ▸ | KLK2 | P20151 | 2/20 | 0.59 |
| ▸ | KLK4 | Q9Y5K2 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563232 | 0.87 | KLK8 (0.63) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL4231397 | 0.82 | KLK8 (0.59) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL916422 | 0.82 | KLK8 (0.59) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL28701098 | 0.81 | KLK8 (0.57) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL916048 | 0.81 | KLK8 (0.57) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL24795803 | 0.79 | LTA4H (0.40) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL6766317 | 0.79 | KLK8 (0.55) | KLK8PLAUKLK2KLK4HPGD | |
| SCHEMBL21840449 | 0.78 | KLK8 (0.55) | KLK8PLAUKLK2KLK4SRC | |
| SCHEMBL13538167 | 0.77 | KLK8 (0.54) | KLK8PLAUKLK2KLK4MAPT | |
| SCHEMBL17923914 | 0.76 | KLK8 (0.53) | KLK8PLAUKLK2KLK4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031639-B | Preparation method of biphospide with P-O-C-P structure | 烟台大学 | 2024-07-12 | — | — | CN | disclosed |