SCHEMBL916061

SCHEMBL916061

CC(C)(C)OC(=O)C[C@H]1C[C@@H](CCN)OC2(CCCCC2)O1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9370192 1.00 MIF (0.33) MIF
SCHEMBL9370199 1.00 MIF (0.33) MIF
SCHEMBL9364969 1.00 MIF (0.33) MIF
SCHEMBL9365409 0.99 MIF (0.33) MIF
SCHEMBL9828916 0.99 MIF (0.33) MIF
SCHEMBL14163368 0.99 MIF (0.33) MIF
SCHEMBL966536 0.87 MIF (0.35) MIF
SCHEMBL12238538 0.87 MIF (0.35) MIF
SCHEMBL9365286 0.87 MIF (0.35) MIF
SCHEMBL916725 0.87 MIF (0.35) MIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2245008-B1 METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN CHONG KUN DANG PHARM CORP (KR) 2013-02-20 EP disclosed
US-8178697-B2 Method for the preparation of atorvastatin and intermediates used therein CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2012-05-15 US disclosed
US-20110015407-A1 METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2011-01-20 US disclosed
EP-2245008-A1 METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN Chong Kun Dang Pharmaceutical Corp. (KR) 2010-11-03 EP disclosed
WO-2009093776-A1 METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN CHONG KUN DANG PHARMACEUTICAL CORP. (KR) 2009-07-30 WO disclosed
WO-2008075165-A1 NOVEL PROCESS FOR THE SYNTHESIS OF [R-(R*, R*)]-2-(4-FLUOROPHENYL)-BETA, DELTA-DIHYDROXY-5-(1-METHYLETHYL)-3-PHENYL-4-[(PHENYLAMINO)CARBONYL]-1H-PYRROLE-1-HEPTANOIC ACID OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF PFIZER PRODUCTS INC. (US) 2008-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110015407-A1 METHOD FOR THE PREPARATION OF ATORVASTATIN AND INTERMEDIATES USED THEREIN HMGCR, PCSK9, CETP MIF 3706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.