Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163368 | 1.00 | MIF (0.33) | MIF | |
| SCHEMBL9828916 | 1.00 | MIF (0.33) | MIF | |
| SCHEMBL916061 | 0.99 | MIF (0.33) | MIF | |
| SCHEMBL9370199 | 0.99 | MIF (0.33) | MIF | |
| SCHEMBL9370192 | 0.99 | MIF (0.33) | MIF | |
| SCHEMBL9364969 | 0.99 | MIF (0.33) | MIF | |
| SCHEMBL966536 | 0.88 | MIF (0.35) | MIF | |
| SCHEMBL12238538 | 0.88 | MIF (0.35) | MIF | |
| SCHEMBL9365286 | 0.88 | MIF (0.35) | MIF | |
| SCHEMBL916725 | 0.88 | MIF (0.35) | MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330172-B1 | Improved process for trans-6-[2-(substituted-pyrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | WARNER LAMBERT CO (US) | 1994-08-10 | — | — | EP | claimed |
| US-5149837-A | Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1992-09-22 | — | — | US | claimed |
| EP-0330172-A2 | Improved process for trans-6-[2-(substituted-pyrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis | WARNER-LAMBERT COMPANY (US) | 1989-08-30 | — | — | EP | claimed |