Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.68 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.68 |
| ▸ | GSK3B | P49841 | 14/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TOP2A | P11388 | 2/20 | 0.55 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9158072 | 1.00 | POLB (0.68) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9157848 | 1.00 | POLB (0.68) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9790134 | 0.97 | POLB (0.69) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL8922019 | 0.93 | POLB (0.72) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9165069 | 0.92 | POLB (0.61) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9159605 | 0.92 | POLB (0.61) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9160778 | 0.92 | POLB (0.61) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| Hydrochloric Acid SCHEMBL9368352 | 0.91 | POLB (0.69) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL10686828 | 0.91 | CACNA1F (0.74) | POLBCACNA1FMAPK1CACNA1DKCNH2 | |
| SCHEMBL9160785 | 0.90 | CACNA1F (0.73) | POLBCACNA1FMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6041084-A | — | — | None | — | — | JP | disclosed |
| US-5430028-A | Strong activity against grampositive bacteria; excellent absorption | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0601197-A1 | 5-AMINOQUINOLONECARBOXYLIC ACID DERIVATIVE AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |
| JP-H0641084-A | 5-AMINOQUINOLONECARBOXYLIC ACID DERIVATIVE AND ANTIMICROBIAL AGENT CONTAINING THE SAME DERIVATIVE AS ACTIVE COMPONENT | SS PHARMACEUT CO LTD | 1994-02-15 | — | — | JP | disclosed |
| JP-H00641084-A | — | — | 0001-01-01 | — | — | JP | disclosed |