Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.73 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.73 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.73 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.73 |
| ▸ | GSK3B | P49841 | 15/20 | 0.66 |
| ▸ | TOP2A | P11388 | 2/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686828 | 0.99 | CACNA1F (0.74) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10542768 | 0.91 | CACNA1F (0.67) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9426331 | 0.90 | CACNA1F (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10412149 | 0.90 | CACNA1F (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL5868656 | 0.90 | POLB (0.71) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10547807 | 0.90 | KCNH2 (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9160633 | 0.90 | POLB (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9158072 | 0.90 | POLB (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9157848 | 0.90 | POLB (0.68) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL10681752 | 0.89 | CACNA1F (0.70) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430028-A | Strong activity against grampositive bacteria; excellent absorption | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0601197-A1 | 5-AMINOQUINOLONECARBOXYLIC ACID DERIVATIVE AND ANTIBACTERIAL CONTAINING THE SAME AS ACTIVE INGREDIENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-06-15 | — | — | EP | disclosed |