Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NEK2 | P51955 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160735 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1PKMHPGDNEK2 | |
| SCHEMBL9161089 | 0.81 | TSHR (0.50) | ALDH1A1HPGDCA12CA1CA2 | |
| SCHEMBL14964565 | 0.79 | MAPT (0.62) | KDM4EALDH1A1HPGDTSHRAHR | |
| SCHEMBL9365521 | 0.76 | CISD1 (0.56) | KDM4EALDH1A1HPGD | |
| SCHEMBL9365514 | 0.76 | CISD1 (0.56) | KDM4EALDH1A1HPGD | |
| SCHEMBL27441056 | 0.75 | KDM4E (0.57) | KDM4EALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL20156660 | 0.75 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL27440551 | 0.75 | NR5A1 (0.50) | KDM4EALDH1A1HPGDTSHRAHR | |
| SCHEMBL13766390 | 0.75 | HPGD (0.46) | KDM4EALDH1A1PKMHPGDNEK2 | |
| SCHEMBL10465934 | 0.74 | NPC1 (0.58) | KDM4EALDH1A1PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5410630-A | Optical article containing a polymer exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (US) | 1995-04-25 | — | — | US | disclosed |