SCHEMBL9160883

SCHEMBL9160883

COc1cc(OC)nc(Oc2cccc(OS(=O)(=O)C(F)(F)F)c2C(=O)OCC[Si](C)(C)C)n1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2C9 P11712 2/20 0.39
CYP2C19 P33261 2/20 0.39
GAA P10253 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9198260 0.84 CYP1A2 (0.44) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9221023 0.83 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9195996 0.83 ALDH1A1 (0.56) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9223126 0.82 CYP1A2 (0.44) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9223119 0.81 CYP1A2 (0.45) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9161257 0.79 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9155892 0.78 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL9155888 0.78 CYP1A2 (0.41) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL28510558 0.77 CYP1A2 (0.47) CYP1A2CYP3A4CYP2C9CYP2C19GAA
SCHEMBL6163867 0.76 NCEH1 (0.39) CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5401711-A Oxygen or sulfur derivatives KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1995-03-28 US disclosed
EP-0555488-A1 PYRIMIDINE OR TRIAZINE DERIVATIVE AND HERBICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-08-18 EP disclosed