Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.31 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | GGH | Q92820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947256 | 0.98 | USP2 (0.34) | USP2ALDH1A1TSHRMAPK1FOLH1 | |
| SCHEMBL9266659 | 0.91 | CA1 (0.35) | USP2ALDH1A1CA2CA1 | |
| SCHEMBL5015012 | 0.84 | CA2 (0.38) | FOLH1RIMKLANAALAD2CA2CA4 | |
| SCHEMBL21490309 | 0.83 | HTT (0.33) | USP2ALDH1A1TSHR | |
| SCHEMBL23248621 | 0.82 | CA2 (0.37) | FOLH1RIMKLANAALAD2CA2CA4 | |
| SCHEMBL8935945 | 0.82 | CA2 (0.37) | FOLH1RIMKLANAALAD2CA2CA4 | |
| SCHEMBL9153082 | 0.78 | MME (0.34) | FOLH1RIMKLANAALAD2CA2CA4 | |
| SCHEMBL9505796 | 0.78 | ECE1 (0.36) | ALDH1A1FOLH1RIMKLANAALAD2CA2 | |
| SCHEMBL10697008 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL9266900 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0637252-A1 | NHR CONTRAST AGENTS | COCKBAIN, Julian Roderick Michaelson (GB) | 1995-02-08 | — | — | EP | disclosed |
| WO-1993021960-A1 | NHR CONTRAST AGENTS | NYCOMED IMAGING AS (NO) | 1993-11-11 | — | — | WO | disclosed |