Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 9/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 3/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77076 | 0.90 | NPC1 (0.55) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10078883 | 0.89 | NPC1 (0.54) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4137597 | 0.89 | NPC1 (0.54) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL77627 | 0.80 | NPC1 (0.59) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10083282 | 0.79 | LMNA (0.58) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL10084855 | 0.78 | LMNA (0.57) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL4127538 | 0.76 | MAPT (0.65) | SMN1; SMN2NPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL10085270 | 0.72 | PDE5A (0.57) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL77371 | 0.71 | KMT2A (0.63) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL78204 | 0.70 | KMT2A (0.62) | LMNASMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | LMNA 2321/4885SMN1; SMN2 4339/4885NPC1 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.