Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586616 | 0.89 | KCNH2 (0.41) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10042881 | 0.88 | NPC1 (0.41) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL3375506 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL987390 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL13990681 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL1170313 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10358429 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL12313748 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10042891 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10042893 | 0.86 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314195-B1 | Electrophotographic sensitive material | MITA INDUSTRIAL CO LTD (JP) | 1995-03-22 | — | — | EP | disclosed |
| US-4877702-A | PERYLENE TYPE ELECTRIC CHARGE GENERATING SUBSTANCE AND DIAMINE DERIVATIVE AS ELECTRIC CHARGE TRANSFERRING SUBSTANCE | MITA INDUSTRIAL CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |
| EP-0314195-A2 | Electrophotographic sensitive material | MITA INDUSTRIAL CO. LTD. (JP) | 1989-05-03 | — | — | EP | disclosed |