Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | BID | P55957 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9167835 | 0.89 | TSHR (0.43) | TSHRBCHETYRACHEPOLB | |
| SCHEMBL9494379 | 0.88 | BID (0.45) | TSHRBCHETYRACHEKDM4E | |
| SCHEMBL9162952 | 0.85 | TSHR (0.48) | TSHRBCHETYRACHEPOLB | |
| SCHEMBL9861545 | 0.83 | TSHR (0.42) | TSHRBCHETYRACHEJUN | |
| SCHEMBL27929073 | 0.83 | GABRA1 (0.53) | TSHRTYRPOLBGABRA1GABRB2 | |
| SCHEMBL69199 | 0.80 | HPGD (0.41) | JUNKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27756509 | 0.78 | TSHR (0.43) | TSHRBCHETYRACHEPOLB | |
| SCHEMBL9173807 | 0.77 | MEN1 (0.42) | TSHRBCHEACHEPOLBJUN | |
| SCHEMBL296591 | 0.76 | TSHR (0.68) | TSHRBCHETYRACHEPOLB | |
| SCHEMBL29860994 | 0.76 | TSHR (0.68) | TSHRBCHETYRACHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431756-B1 | Polyol and rigid polyurethane foam | MITSUI TOATSU CHEMICALS (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5246978-A | Thermal insulation material; epoxy resin based, phenolic resin based or aromatic amine based polyol component | MITSUI TOATSU CHEMICALS, INC. (JP) | 1993-09-21 | — | — | US | disclosed |
| EP-0431756-A2 | Polyol and rigid polyurethane foam | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1991-06-12 | — | — | EP | disclosed |