Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 7/20 | 0.76 |
| ▸ | KDM4A | O75164 | 3/20 | 0.76 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.76 |
| ▸ | SIRT3 | Q9NTG7 | 11/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | KDM7A | Q6ZMT4 | 2/20 | 0.73 |
| ▸ | THRA | P10827 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | MLNR | O43193 | 1/20 | 0.73 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.73 |
| ▸ | PHF2 | O75151 | 1/20 | 0.73 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.73 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165920 | 0.90 | THRA (0.82) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL25873319 | 0.89 | KDM5A (0.86) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL19895690 | 0.88 | KDM5A (0.85) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL19895688 | 0.88 | THRA (0.83) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL10670973 | 0.87 | SIRT3 (0.82) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL7242769 | 0.87 | KDM5A (1.00) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL28313449 | 0.87 | KDM5A (0.82) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL19077706 | 0.86 | KDM5A (0.77) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL23682805 | 0.85 | SIRT3 (1.00) | KDM5AKDM4AING2SIRT3ABCB1 | |
| SCHEMBL23682665 | 0.85 | SIRT3 (0.93) | KDM5AKDM4AING2SIRT3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399672-A | Process for preparing immunoconjugates | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-03-21 | — | — | US | disclosed |
| EP-0599142-A2 | Method for making immuno-conjugates | MERCK PATENT GmbH (DE) | 1994-06-01 | — | — | EP | disclosed |
| EP-0599141-A2 | Means and process for immunological determination of amiodarone and its metabolites | MERCK PATENT GmbH (DE) | 1994-06-01 | — | — | EP | disclosed |