SCHEMBL9162807

SCHEMBL9162807

CCCCCCCCNc1cccc2c(N)cccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.49
CNR2 P34972 1/20 0.49
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 2/20 0.44
KDM4E B2RXH2 1/20 0.44
GAA P10253 1/20 0.44
NPSR1 Q6W5P4 2/20 0.42
S1PR2 O95136 1/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
CYP3A4 P08684 1/20 0.42
IDO1 P14902 1/20 0.41
HTR1A P08908 2/20 0.41
ADRA1D P25100 2/20 0.41
ADRA1A P35348 2/20 0.41
ADRA1B P35368 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23346286 0.90 CNR1 (0.56) CNR1CNR2ALDH1A1HPGDTSHR
SCHEMBL30069294 0.90 CNR1 (0.56) CNR1CNR2ALDH1A1HPGDTSHR
SCHEMBL30069272 0.88 CNR1 (0.57) CNR1CNR2ALDH1A1HPGDTSHR
SCHEMBL8088625 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL9011310 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL7365605 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL9168077 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL8082845 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL21799596 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2
SCHEMBL7970465 0.83 L3MBTL1 (0.48) CNR2NPSR1S1PR2LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0512954-B1 Substituted naphthalenediamine stabilizers CIBA GEIGY AG (CH) 1995-03-08 EP disclosed
US-5198134-A Antioxidants for lubricants CIBA-GEIGY CORPORATION (US) 1993-03-30 US disclosed
EP-0512954-A1 Substituted naphthalenediamine stabilizers CIBA-GEIGY AG (CH) 1992-11-11 EP disclosed