SCHEMBL9163063

SCHEMBL9163063

O=C(O)C(=C(F)F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.56
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083022 1.00 THRB (0.56) THRBCA1CA2MMP1MMP2
SCHEMBL29859185 1.00 THRB (0.56) THRBCA1CA2MMP1MMP2
SCHEMBL528802 1.00 THRB (0.56) THRBCA1CA2MMP1MMP2
SCHEMBL15956620 1.00 THRB (0.56) THRBCA1CA2MMP1MMP2
SCHEMBL1253926 1.00 THRB (0.56) THRBCA1CA2MMP1MMP2
SCHEMBL1736485 0.98 THRB (0.52) THRB
SCHEMBL4341497 0.91 THRB (0.67) THRBCA1CA2MMP1MMP2
SCHEMBL2401748 0.91 THRB (0.67) THRBCA1CA2MMP1MMP2
SCHEMBL12095169 0.91 THRB (0.67) THRBCA1CA2MMP1MMP2
SCHEMBL2401754 0.91 THRB (0.67) THRBCA1CA2MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0373923-B1 High light-transmissive dust-proof body and method of preparing same MITSUI PETROCHEMICAL IND (JP) 1995-03-01 EP disclosed
US-5246767-A HIGH LIGHT-TRANSMISSIVE DUST-PROOF BODY AND METHOD OF PREPARING SAME MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-09-21 US disclosed
EP-0373923-A2 High light-transmissive dust-proof body and method of preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-06-20 EP disclosed
EP-0103436-A2 Process for preparing 5-perfluoroalkyl-5,6-dihydrouracil derivatives and compounds for use therein SAGAMI CHEMICAL RESEARCH CENTER (JP) 1984-03-21 EP disclosed