Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 7/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072938 | 1.00 | DRD2 (0.38) | DRD2DRD3CYP2D6DRD1LMNA | |
| SCHEMBL9728792 | 1.00 | DRD2 (0.38) | DRD2DRD3CYP2D6DRD1LMNA | |
| SCHEMBL10409965 | 1.00 | DRD2 (0.38) | DRD2DRD3CYP2D6DRD1LMNA | |
| SCHEMBL11072940 | 1.00 | DRD2 (0.38) | DRD2DRD3CYP2D6DRD1LMNA | |
| SCHEMBL11190432 | 0.91 | DRD3 (0.30) | DRD2DRD3CYP2D6 | |
| SCHEMBL11190402 | 0.91 | DRD3 (0.30) | DRD2DRD3CYP2D6 | |
| SCHEMBL9729123 | 0.87 | DRD2 (0.37) | DRD2DRD3CYP2D6DRD1LMNA | |
| SCHEMBL10562020 | 0.87 | DRD2 (0.37) | DRD2DRD3CYP2D6DRD1LMNA | |
| Maleic Acid SCHEMBL11067867 | 0.82 | DRD2 (0.32) | DRD2DRD3CYP2D6DRD1LMNA | |
| Maleic Acid SCHEMBL11067872 | 0.82 | DRD2 (0.32) | DRD2DRD3CYP2D6DRD1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5416090-A | Ergoline analogues | ELI LILLY AND COMPANY (US) | 1995-05-16 | — | — | US | disclosed |