Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27687659 | 0.92 | ALDH1A1 (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL167047 | 0.82 | ALDH1A1 (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL24649555 | 0.82 | TSHR (0.44) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL6655502 | 0.80 | TSHR (0.47) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL11332040 | 0.78 | KMT2A (0.39) | TSHRALDH1A1SMN1; SMN2KDM4ERAB9A | |
| SCHEMBL12515388 | 0.78 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30263675 | 0.76 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL30263676 | 0.75 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19146018 | 0.75 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL20733275 | 0.75 | SMN1; SMN2 (0.49) | ALDH1A1HPGDSMN1; SMN2MAPTGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432920-B1 | Polymer-modified cements with improved chemical resistance | ROHM & HAAS (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5162060-A | Acrylic Polymer Containing Ureido Group, Epoxy Resin | ROHM AND HAAS COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0432920-A2 | Polymer-modified cements with improved chemical resistance | ROHM AND HAAS COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4190693-A | WATERBASE, THERMOSETTING RESINS FOR DIRECT ROLL COATING | ROHM AND HAAS COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4126595-A | Aqueous coating compositions comprising acrylic oligomers, high molecular weight polymers and crosslinkers | ROHM AND HAAS COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4087397-A | Aqueous coating compositions comprising acrylic oligomers and high molecular weight polymers | ROHM AND HAAS COMPANY (US) | 1978-05-02 | — | — | US | disclosed |