SCHEMBL9163909

SCHEMBL9163909

CCCCCCCCCCCCCCCCCCNC(N)CCCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.46
SPHK1 Q9NYA1 2/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
EPHX1 P07099 2/20 0.42
TP53 P04637 2/20 0.42
RRM1 P23921 1/20 0.42
DPP7 Q9UHL4 2/20 0.41
CYP2D6 P10635 2/20 0.41
PLA2G1B P04054 1/20 0.41
PLA2G2A P14555 1/20 0.41
GMNN O75496 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41
BLM P54132 1/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28161008 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL28196519 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL28331825 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL27457477 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL28542120 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL28985254 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL9691923 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL27146358 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL28116311 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1
SCHEMBL27296398 1.00 OPRM1 (0.46) OPRM1SPHK1GNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112584879-B Lubrication method 小太阳公司 2022-10-11 CN disclosed
CN-103288832-A Pyrrolopyridazine compounds with antiviral properties ASCLETIS HANGZHOU CO LTD 2013-09-11 CN disclosed
CN-101909736-B Catalyst feeding system and application method thereof UNIVATION TECH LLC 2013-09-04 CN disclosed
CN-103254129-A Intergrase inhibitor SHIFANG PHARMACY HANGZHOU CO LTD 2013-08-21 CN disclosed
CN-102686575-A Modulators of G-protein coupled receptor 88 BRISTOL MYERS SQUIBB CO 2012-09-19 CN disclosed
CN-101568336-B Use of macrocyclic peptides for the preparation of hepatitis c virus inhibitors BRISTOL MYERS SQUIBB CO 2012-07-04 CN disclosed
CN-101568543-B Macrocyclic peptides as hepatitis c virus inhibitors BRISTOL MYERS SQUIBB CO 2012-06-06 CN disclosed
CN-102199216-A New dendritic cell co-stimulatory molecules UNIV JOHNS HOPKINS 2011-09-28 CN disclosed
CN-101065452-B Process for making perylene pigment compositions SUN CHEMICAL CORP 2011-07-27 CN disclosed
CN-1688695-B Novel Dendritic Cell Costimulatory Molecules JOHNS HOPKINS UNIVERCITY 2011-05-11 CN disclosed
CN-1322518-C Conductive paste for terminal electrode of multilayer ceramic electronic part SHOEI CHEMICAL IND CO (JP) 2007-06-20 CN disclosed
CN-1295240-C Intermediate for preparing 4' -substituted 9-deoxy-9A-aza-9A-homoerythromycin A derivative and preparation method thereof PFIZER (US) 2007-01-17 CN disclosed
CN-1700361-A Conductive paste for terminal electrode of multilayer ceramic electronic part SHOEI CHEMICAL IND CO (JP) 2005-11-23 CN disclosed
CN-1688695-A Novel Dendritic Cell Costimulatory Molecules UNIV JOHNS HOPKINS (US) 2005-10-26 CN disclosed
CN-1530370-A Intermediate for preparing 4' -substituted 9-deoxy-9A-aza-9A-homoerythromycin A derivative and preparation method thereof �Ʒ� 2004-09-22 CN disclosed
CN-1167708-C Method for preparing 4' -substituted 9-deoxy-9A-aza-9A-homoerythromycin A derivative �Ʒ� 2004-09-22 CN disclosed
CN-1384108-A Method for preparing 4' -substituted 9-deoxy-9A-aza-9A-homoerythromycin A derivative PFIZER PRODUCT CO (US) 2002-12-11 CN disclosed
EP-0525157-B1 FUEL COMPOSITION LUBRIZOL CORP (US) 1995-03-01 EP disclosed
EP-0525157-A1 FUEL COMPOSITION. LUBRIZOL CORP (US) 1993-02-03 EP disclosed
WO-1992014805-A1 FUEL COMPOSITION THE LUBRIZOL CORPORATION (US) 1992-09-03 WO disclosed