⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98 | 0.77 | — | — | |
| SCHEMBL6704332 | 0.77 | TP53 (0.31) | — | |
| Water SCHEMBL1292893 | 0.71 | — | — | |
| SCHEMBL10946713 | 0.71 | — | — | |
| SCHEMBL2061532 | 0.71 | — | — | |
| SCHEMBL6068389 | 0.71 | — | — | |
| Lithium SCHEMBL11132311 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL17188187 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL2812912 | 0.71 | — | — | |
| SCHEMBL31544526 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116535420-A | Synthesis method of 5, 6-dichloro furazano [3,4-b ] pyrazine | 西安近代化学研究所 | 2023-08-04 | — | — | CN | disclosed |
| US-5442060-A | Treating hyperlipemia, atherosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0591830-A1 | Carboxamide and urea derivatives having ACAT-inhibiting activityM | Mitsubishi Chemical Corporation (JP) | 1994-04-13 | — | — | EP | disclosed |