Hydrochloric Acid

Hydrochloric Acid

SCHEMBL2812912

Cl.O=P(Cl)(Cl)Cl

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28130960 1.00
Hydrochloric Acid SCHEMBL4806073 1.00
SCHEMBL6704332 0.93 TP53 (0.31)
SCHEMBL98 0.93
SCHEMBL6068389 0.86
SCHEMBL10946713 0.86
SCHEMBL31398318 0.86
Ammonia Solution, Strong SCHEMBL17188187 0.86
Water SCHEMBL1292893 0.86
Lithium SCHEMBL11132311 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106565773-B A kind of preparation method of high-purity phosphoric acid ester fire retardant tricresyl phosphate (2- chloropropyl) ester 泰州瑞世特新材料有限公司 2019-06-14 CN claimed
CN-105924625-B A kind of water white transparency Halogenless fire retarded epoxy resin of low-temperature curable and preparation method thereof 长春工业大学 2018-08-24 CN claimed
CN-105924626-B A kind of halogen-free flameproof curing agent of liquid water white transparency epoxy resin and preparation method thereof 长春工业大学 2018-06-19 CN claimed
CN-107722054-A A kind of vitamin D3Phosphamide and preparation method thereof 无锡福祈制药有限公司 2018-02-23 CN claimed
CN-107629248-A A kind of agent of hyperbranched expandable flame retardant containing phosphine oxide and its preparation method and application 中国科学技术大学 2018-01-26 CN claimed
CN-105482430-B A kind of method that utilization sol-gal process prepares polyethylene glycol phase-change material 西南科技大学 2017-10-03 CN claimed
CN-105131037-B Preparation method for high-purity tedizolid phosphate 济南爱思医药科技有限公司 2017-05-03 CN claimed
CN-106279716-A A kind of P Modification hydroxymethylated lignin carbon forming agent and preparation method thereof 常州大学 2017-01-04 CN claimed
CN-102077060-B Monitoring system based on corrosion metal G. PATEL (US) 2014-10-29 CN claimed
CN-1055535-A Synthesizing of 2-hydroxy-n-methyl-N-phenyl-6-naphthalene sulfonylamide KE BAOGUI (CN) 1991-10-23 CN claimed
EP-4724070-A2 WRN INHIBITORS Nimbus Wadjet, Inc. (US) 2026-04-15 EP disclosed
WO-2024254511-A2 WRN INHIBITORS NIMBUS WADJET, INC. (US) 2024-12-12 WO disclosed
CN-107188898-B Process for preparing thienopyrimidine compounds 霍夫曼-拉罗奇有限公司 2019-12-03 CN disclosed
CN-105980384-B Macrocyclic compounds having a heterocyclic P2' group as factor XIA inhibitors 百时美施贵宝公司 2019-11-15 CN disclosed
CN-105705492-B 5,6,7, 8-tetrahydro-5, 8-methanocinnoline derivatives as RORC modulators for the treatment of autoimmune diseases 豪夫迈·罗氏有限公司 2019-11-05 CN disclosed
CN-1220029-A Incombustible/self-extinguishing battery electrolyte STANFORD RES INST INT (US) 1999-06-16 CN disclosed
CN-1179713-A Use of LCK SH2 specific compounds to treat autoimmune diseases and allograft rejection SMITHKLINE BEECHAM CORP (US) 1998-04-22 CN disclosed
WO-1997048279-A1 AGENTS WITH ANTIFUNGAL ACTIVITY AND METHODS OF USE THEREOF UNIVERSITY OF ALBERTA (US) 1997-12-24 WO disclosed
CN-1055535-A Synthesizing of 2-hydroxy-n-methyl-N-phenyl-6-naphthalene sulfonylamide KE BAOGUI (CN) 1991-10-23 CN disclosed
CN-1055535-A Synthesizing of 2-hydroxy-n-methyl-N-phenyl-6-naphthalene sulfonylamide KE BAOGUI (CN) 1991-10-23 CN disclosed