Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | FYN | P06241 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9164083 | 1.00 | HTT (0.78) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL9817747 | 0.99 | HTT (0.76) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL9817744 | 0.99 | HTT (0.76) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL19505658 | 0.89 | HTT (1.00) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL11266237 | 0.88 | HTT (0.72) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL22192868 | 0.88 | LMNA (0.67) | HTTSMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL22222297 | 0.84 | KMT2A (0.66) | SMN1; SMN2MEN1KMT2APOLBATM | |
| SCHEMBL11804567 | 0.84 | SMN1; SMN2 (0.55) | HTTSMN1; SMN2MEN1KMT2AATM | |
| SCHEMBL9160205 | 0.83 | ATM (0.59) | HTTSMN1; SMN2KMT2AKCNH2POLB | |
| Hydrochloric Acid SCHEMBL28898436 | 0.83 | KCNH2 (0.56) | HTTSMN1; SMN2MEN1KMT2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443606-B1 | 4-(4-alkoxyphenyl)-2-butylamine derivatives and process therefor | SHIONOGI & CO (JP) | 1995-05-10 | — | — | EP | disclosed |