Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 11/20 | 0.54 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3497505 | 0.84 | GRM7 (0.43) | ESR1ESR2LMNAKMT2APTGS2 | |
| SCHEMBL1033377 | 0.82 | PTGS2 (0.47) | MAPTSMN1; SMN2CYP2D6PTGS1DRD3 | |
| SCHEMBL11749792 | 0.76 | ESR1 (0.56) | ESR1ESR2PDCD1CD274MAPT | |
| SCHEMBL28228309 | 0.75 | ESR1 (0.46) | ESR1ESR2PDCD1CD274MAPT | |
| SCHEMBL288003 | 0.74 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL892055 | 0.74 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL5794522 | 0.74 | ESR1 (0.54) | ESR1ESR2PDCD1CD274MAPT | |
| SCHEMBL1345582 | 0.74 | PTGS2 (0.63) | ESR1ESR2PDCD1CD274CYP3A4 | |
| SCHEMBL9233559 | 0.73 | HTT (0.44) | ESR1ESR2PDCD1CD274MAPT | |
| SCHEMBL9230521 | 0.73 | HTT (0.44) | ESR1ESR2PDCD1CD274MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354548-B1 | Signal enhancement in assay for an enzyme | BECTON DICKINSON CO (US) | 1995-03-01 | — | — | EP | disclosed |
| EP-0354548-A2 | Signal enhancement in assay for an enzyme | Becton, Dickinson and Company (US) | 1990-02-14 | — | — | EP | disclosed |