SCHEMBL9165704

SCHEMBL9165704

NNC(=O)COc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.49
KDM4E B2RXH2 8/20 0.49
KMT2A Q03164 6/20 0.46
GAA P10253 1/20 0.46
MEN1 O00255 5/20 0.45
MAPT P10636 6/20 0.43
APAF1 O14727 1/20 0.43
G6PD P11413 1/20 0.43
PABPC1 P11940 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
SAE1 Q9UBE0 1/20 0.43
UBA2 Q9UBT2 1/20 0.43
LMNA P02545 1/20 0.43
HPGD P15428 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
POLB P06746 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9291679 0.88 MAPT (0.45) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL9164146 0.88 MAPT (0.51) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL9379689 0.88 MAPT (0.47) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL9504045 0.85 PTPN7 (0.50) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL9061768 0.84 MAPT (0.45) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL9291510 0.83 MAPT (0.39) ALDH1A1KDM4EKMT2AMEN1MAPT
SCHEMBL27749975 0.80 HPGD (0.56) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL6474039 0.79 NPC1 (0.45) ALDH1A1KDM4EMAPTLMNAHPGD
SCHEMBL2729117 0.79 KMT2A (0.47) ALDH1A1KDM4EKMT2AGAAMEN1
SCHEMBL8854056 0.78 NPC1 (0.44) ALDH1A1KDM4EMAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0370501-B1 Polymer bound light stabilizer coating resins ATOCHEM NORTH AMERICA (US) 1995-04-05 EP disclosed
EP-0308886-B1 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA (US) 1994-11-23 EP disclosed
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
EP-0303986-B1 MULTIPURPOSE POLYMER BOUND STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1992-07-29 EP disclosed
US-5096974-A Reacting primary amino or hydrazido-substituted stabilizers with maleic anhydride polymers; nonextractable and nonvolatile in polymer blends ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981915-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4975494-A USING HYDRAZIDE COMPOUND ATOCHEM OF NORTH AMERICA, INC. (US) 1990-12-04 US disclosed
EP-0370501-A2 Polymer bound light stabilizer coating resins ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-05-30 EP disclosed
US-4927891-A REACTING LIGHT STABILIZER HYDRAZIDES WITH ACRYLIC RESINS PENNWALT CORPORATION (US) 1990-05-22 US disclosed
US-4874803-A HEAT AND OXIDATION RESISTANCE; PHOTOSTABILITY PENNWALT CORPORATION (US) 1989-10-17 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
US-4863999-A IMIDES OR AMIC ACIDS OF ANHDRIDE POLYMERS PENNWALT CORPORATION (US) 1989-09-05 US disclosed
EP-0308886-A2 Dianhydride coupled polymer stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-03-29 EP disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed
EP-0303986-A2 Multipurpose polymer bound stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed