SCHEMBL9504045

SCHEMBL9504045

O=C(O)COc1ccc(-n2nc3ccccc3n2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 2/20 0.50
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MAPT P10636 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
HPGD P15428 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
ALOX15 P16050 1/20 0.46
ACACA Q13085 1/20 0.44
PPARD Q03181 2/20 0.44
PPARG P37231 1/20 0.44
FFAR1 O14842 2/20 0.43
LMNA P02545 3/20 0.43
POLB P06746 1/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
PTPN12 Q05209 1/20 0.42
CYSLTR2 Q9NS75 1/20 0.42
CYSLTR1 Q9Y271 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9061768 0.88 MAPT (0.45) PTPN7ALDH1A1KDM4EMAPTNPC1
SCHEMBL29204751 0.86 CYSLTR2 (0.50) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL9165704 0.85 ALDH1A1 (0.49) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL9291679 0.85 MAPT (0.45) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL27749975 0.84 HPGD (0.56) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL7532670 0.83 LMNA (0.50) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL6474039 0.83 NPC1 (0.45) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL2729117 0.83 KMT2A (0.47) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL8854056 0.82 NPC1 (0.44) ALDH1A1KDM4EMAPTNPC1RAB9A
SCHEMBL29510512 0.82 KDM4E (0.52) ALDH1A1KDM4EMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303988-B1 POLYMER BOUND UV STABILIZERS ATOCHEM NORTH AMERICA, INC. (US) 1993-05-12 EP disclosed
US-5206378-A Ultraviolet light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-04-27 US disclosed
US-5096977-A Anhydride polymers ATOCHEM NORTH AMERICA, INC. (US) 1992-03-17 US disclosed
US-4981914-A HYDRAZIDE MODIFIERS ATOCHEM NORTH AMERICA, INC. (US) 1991-01-01 US disclosed
US-4868246-A PRIMARY AMINO OR HYDRAZIDO UV ABSORBERS CHEMICALLY BOUND TO POLYMER ANHYDRIDE GROUPS PENNWALT CORPORATION (US) 1989-09-19 US disclosed
EP-0303988-A2 Polymer bound UV stabilizers ATOCHEM NORTH AMERICA, INC. (US) 1989-02-22 EP disclosed