Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9170915 | 0.84 | TP53 (0.48) | TACR1SLC18A3L3MBTL1 | |
| SCHEMBL22002721 | 0.78 | TSHR (0.41) | PKM | |
| SCHEMBL21558169 | 0.77 | SLC18A3 (0.44) | SLC18A3 | |
| SCHEMBL8391238 | 0.76 | SLC18A3 (0.45) | TACR1SLC18A3 | |
| SCHEMBL8706022 | 0.76 | SLC18A3 (0.45) | TACR1SLC18A3 | |
| SCHEMBL8391240 | 0.76 | SLC18A3 (0.45) | TACR1SLC18A3 | |
| SCHEMBL18088735 | 0.74 | TP53 (0.43) | POLBSLC18A3L3MBTL1 | |
| SCHEMBL1709387 | 0.73 | SSTR3 (0.44) | — | |
| SCHEMBL9164285 | 0.72 | TACR1 (0.79) | TACR1 | |
| SCHEMBL10033109 | 0.72 | KDM1A (0.41) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387595-A | Antiinflammatory agents | MERCK & CO., INC. (US) | 1995-02-07 | — | — | US | disclosed |
| WO-1994004487-A1 | ALICYCLIC COMPOUNDS AS TACHYKININ RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-03-03 | — | — | WO | disclosed |