Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 7/20 | 0.44 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709386 | 0.89 | MAOA (0.48) | MAOAKDM1AMAOB | |
| SCHEMBL1709391 | 0.88 | SSTR3 (0.46) | SSTR3MAOAKDM1AMAOB | |
| SCHEMBL1709392 | 0.83 | MAOA (0.44) | SSTR3MAOAKDM1AMAOBKDM4E | |
| SCHEMBL1709388 | 0.83 | MAOA (0.45) | MAOAKDM1AMAOB | |
| SCHEMBL10033000 | 0.79 | KDM1A (0.44) | SSTR3MAOAKDM1AMAOBKDM4E | |
| SCHEMBL1709467 | 0.75 | TACR1 (0.41) | AGERMTNR1ASLC6A4 | |
| SCHEMBL9166296 | 0.73 | POLB (0.40) | — | |
| SCHEMBL8700543 | 0.72 | KDM1A (0.47) | MAOAKDM1AMAOB | |
| SCHEMBL11433843 | 0.71 | ALDH1A1 (0.40) | KDM4EGAA | |
| SCHEMBL11433840 | 0.71 | ALDH1A1 (0.40) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046771-A1 | CYCLOALKANE COMPOUND | アステラス製薬株式会社 (JP) | 2012-04-12 | — | — | WO | disclosed |