⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15095831 | 0.74 | — | — | |
| SCHEMBL19055557 | 0.69 | — | — | |
| SCHEMBL20381622 | 0.69 | — | — | |
| SCHEMBL7323335 | 0.69 | — | — | |
| SCHEMBL11829929 | 0.67 | — | — | |
| SCHEMBL11787809 | 0.66 | — | — | |
| SCHEMBL18567263 | 0.64 | ADH1B (0.32) | — | |
| SCHEMBL31315650 | 0.64 | — | — | |
| SCHEMBL18587945 | 0.63 | — | — | |
| SCHEMBL8484104 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464844-A | [3H,7H]thiazole[3,4-a]pyridines having antiasthmatic and antiinflammatory activities on the respiratory tract | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-11-07 | — | — | US | disclosed |
| EP-0536169-B1 | [3H,7H]THIAZOLO [3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-04-05 | — | — | EP | disclosed |
| US-5336676-A | [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-08-09 | — | — | US | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| CN-1057263-A | [3H, 7H] thiazole that respiratory tract is had anti-asthma and an anti-inflammatory effect is [3,4-α] pyridine also | BOEHRINGER MANNHEIM ITALIA (IT) | 1991-12-25 | — | — | CN | disclosed |
| WO-1991018906-A1 | [3H,7H]THIAZOLO[3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-12-12 | — | — | WO | disclosed |