Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175879 | 0.91 | TDP1 (0.65) | TDP1LMNACYP2A6CES2CES1 | |
| SCHEMBL11078484 | 0.83 | TSHR (0.56) | LMNACYP2A6CES2CES1TSHR | |
| SCHEMBL9174495 | 0.72 | TDP1 (0.55) | TDP1CES2CES1TSHRKMT2A | |
| SCHEMBL159450 | 0.71 | TDP1 (0.76) | TDP1CES2CES1TSHRALOX15 | |
| SCHEMBL9167331 | 0.67 | TDP1 (1.00) | TDP1LMNACES2ALOX15KMT2A | |
| SCHEMBL9173022 | 0.67 | CA1 (0.52) | TDP1CYP2A6CES2CES1CA1 | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.67 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.67 | — | — | |
| SCHEMBL22999953 | 0.65 | KDM4E (0.72) | TDP1LMNATSHRALOX15KMT2A | |
| SCHEMBL9173936 | 0.65 | TDP1 (0.65) | TDP1CES2CES1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496562-B1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-03-29 | — | — | EP | disclosed |
| US-5310944-A | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0496562-A1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-07-29 | — | — | EP | disclosed |