Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA4 | P22748 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA3 | P07451 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159450 | 0.87 | TDP1 (0.76) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9173936 | 0.79 | TDP1 (0.65) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9176147 | 0.79 | TDP1 (0.65) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9175879 | 0.79 | TDP1 (0.65) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9177404 | 0.79 | TDP1 (0.65) | TDP1KMT2ACA4CA9CA14 | |
| Phenol SCHEMBL27865365 | 0.76 | CA9 (0.69) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9176757 | 0.74 | TDP1 (0.59) | TDP1CA4CA9CA14CA6 | |
| SCHEMBL9177348 | 0.74 | TDP1 (0.59) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9174936 | 0.74 | TDP1 (0.59) | TDP1KMT2ACA4CA9CA14 | |
| SCHEMBL9176214 | 0.74 | TDP1 (0.59) | TDP1KMT2ACA4CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496562-B1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-03-29 | — | — | EP | disclosed |
| US-5310944-A | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0496562-A1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-07-29 | — | — | EP | disclosed |