Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159450 | 0.85 | TDP1 (0.76) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9167331 | 0.79 | TDP1 (1.00) | TDP1CA4CA6CA7CA9 | |
| Toluene SCHEMBL27285671 | 0.78 | ACHE (0.65) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9175879 | 0.77 | TDP1 (0.65) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9176147 | 0.77 | TDP1 (0.65) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9173936 | 0.77 | TDP1 (0.65) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9174936 | 0.77 | TDP1 (0.59) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL9176757 | 0.77 | TDP1 (0.59) | TDP1CA4CA6CA7CA9 | |
| SCHEMBL11034243 | 0.75 | TSHR (0.56) | TDP1CA4CA6CA7CA9 | |
| Toluene SCHEMBL28752867 | 0.73 | ACHE (0.58) | TDP1CA4CA6CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0496562-B1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL CO (JP) | 1995-03-29 | — | — | EP | disclosed |
| US-5310944-A | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0496562-A1 | Process for producing carboxylated compound | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-07-29 | — | — | EP | disclosed |