SCHEMBL916741

SCHEMBL916741

OCc1ccno1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9553682 0.80
SCHEMBL7045074 0.76
SCHEMBL5848314 0.74
SCHEMBL356231 0.74
SCHEMBL1752092 0.74
SCHEMBL5263447 0.74
Hydrochloric Acid SCHEMBL5212534 0.72
SCHEMBL1650609 0.72
SCHEMBL17984802 0.70
SCHEMBL5847916 0.70 PGK1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9139567-B2 Arylpyrazole ethers as inhibitors of leukotriene A4 hydrolase BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-09-22 US claimed
CN-102558083-B Synthesizing method for N, N-double substitution-3-amino isoxazole-5-methanol compound WUXI APPTEC CO LTD 2015-07-01 CN claimed
US-20140221373-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2014-08-07 US claimed
EP-2734516-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE Boehringer Ingelheim International GmbH (DE) 2014-05-28 EP claimed
WO-2013012844-A1 ARYLPYRAZOLE ETHERS AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2013-01-24 WO claimed
CN-102558083-A Synthesizing method for N, N-double substitution-3-amino isoxazole-5-methanol compound WUXI APPTEC CO LTD 2012-07-11 CN claimed
EP-0028355-B1 1,2-OXAZOLYLALKYL CARBAMATES, THEIR PREPARATION, THEIR USE AS HERBICIDES, AND HERBICIDES BASF Aktiengesellschaft (DE) 1984-05-09 EP claimed
EP-0028355-A1 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides BASF Aktiengesellschaft (DE) 1981-05-13 EP claimed
JP-1050871-A None JP disclosed
US-12637468-B2 Substituted [1,2,4]triazolo[4,3-b]pyridazines as GABAA receptor modulators Shanghai Simr Biotechnology Co., Ltd. (CN) 2026-05-26 US disclosed
US-20260137703-A1 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER CANCER RESEARCH TECH LIMITED (GB) 2026-05-21 US disclosed
US-20260116887-A1 HETEROCYCLIC COMPOUNDS FOR MEDIATING TYROSINE KINASE 2 ACTIVITY GUANGZHOU INNOCARE PHARMA TECH CO LTD (CN) 2026-04-30 US disclosed
EP-4695238-A1 CDK2 INHIBITORS Blueprint Medicines Corporation (US) 2026-02-18 EP disclosed
US-12545684-B2 CDK2 inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2026-02-10 US disclosed
EP-0486948-A2 Retroviral protease inhibiting compounds ABBOTT LABORATORIES (US) 1992-05-27 EP disclosed
EP-0302491-A1 5-Formyl-isoxazoles BASF Aktiengesellschaft (DE) 1989-02-08 EP disclosed
EP-0028355-B1 1,2-OXAZOLYLALKYL CARBAMATES, THEIR PREPARATION, THEIR USE AS HERBICIDES, AND HERBICIDES BASF Aktiengesellschaft (DE) 1984-05-09 EP disclosed
EP-0087953-A2 Antibacterial 1-normon-2-yl-heterocyclic compounds BEECHAM GROUP PLC (GB) 1983-09-07 EP disclosed
US-4385924-A 1,2-Oxazolyl alkyl carbamates, and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1983-05-31 US disclosed
EP-0028355-A1 1,2-Oxazolylalkyl carbamates, their preparation, their use as herbicides, and herbicides BASF Aktiengesellschaft (DE) 1981-05-13 EP disclosed