SCHEMBL916780

SCHEMBL916780

CCOP(=O)(Cc1ccc(C(=O)OC)c2ccccc12)OCC

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 2/20 0.46
NR4A2 P43354 4/20 0.44
CNR1 P21554 2/20 0.43
LMNA P02545 6/20 0.41
GAA P10253 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CREBBP Q92793 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EGFR P00533 1/20 0.38
PLK1 P53350 1/20 0.38
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL915622 0.89 BRD4 (0.46) BRD4NR4A2CNR1LMNAGAA
SCHEMBL915976 0.86 CYP2C9 (0.41) NR4A2MAPTHTTEGFR
SCHEMBL11740510 0.85 BRD4 (0.44) BRD4NR4A2CNR1LMNAGAA
SCHEMBL11751939 0.84 KDM4E (0.44) LMNAKDM4EMAPTHPGDEGFR
SCHEMBL914622 0.83 ALDH1A1 (0.51) BRD4NR4A2LMNAGAAKDM4E
SCHEMBL916005 0.83 ACP3 (0.49) BRD4NR4A2CNR1LMNAGAA
SCHEMBL12419944 0.81 BRD4 (0.53) BRD4NR4A2CNR1LMNAGAA
SCHEMBL31497570 0.78 BRD4 (0.49) BRD4NR4A2CNR1LMNAGAA
SCHEMBL2650431 0.78 BRD4 (0.49) BRD4NR4A2CNR1LMNAGAA
SCHEMBL914957 0.78 HPGD (0.38) BRD4NR4A2LMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7868126-B2 Process for producing polyester, polyester produced using said process, and polyester molded product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2011-01-11 US disclosed
EP-1842868-B1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT TOYO BOSEKI (JP) 2010-11-10 EP disclosed
US-20090082529-A1 Polyester, Process for Producing Polyester, and Polyester Molded Article TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-03-26 US disclosed
US-20080249280-A1 Process for Producing Polyester, Polyester Produced Using Said Process, and Polyester Molded Product TOYO BOSEKI KABUSHIKI KAISHA (JP) 2008-10-09 US disclosed
EP-1932867-A1 POLYESTER, PROCESS FOR PRODUCTION OF POLYESTER, AND POLYESTER MOLDED ARTICLE Toyo Boseki Kabushiki Kasisha (JP) 2008-06-18 EP disclosed
EP-1842868-A1 PROCESS FOR PRODUCING POLYESTER, POLYESTER PRODUCED USING SAID PROCESS, AND POLYESTER MOLDED PRODUCT Toyo Boseki Kabushiki Kasisha (JP) 2007-10-10 EP disclosed