Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | BCHE | P06276 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | CES2 | O00748 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | PDE6D | O43924 | 1/20 | 0.47 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Isatin SCHEMBL1897654 | 0.91 | CES1 (0.83) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL30951976 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL20721761 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL29506688 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL14830555 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL5352173 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL2348974 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL14830299 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL2305737 | 0.85 | CES1 (0.73) | CES1ALDH1A1BCHENPSR1CES2 | |
| SCHEMBL18020245 | 0.82 | CES1 (0.69) | CES1ALDH1A1BCHENPSR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | claimed |
| CN-103435621-B | Spiro quinazoline derivative and preparation method thereof | INSTITUTE OF CHEMICAL INDUSTRY OF FOREST PRODUCTS, CHINESE ACADEMY OF FORESTRY (CN) | 2015-11-04 | — | — | CN | claimed |
| CN-103539720-A | Method for preparing 1-phenylindole | UNIV CHANGZHOU | 2014-01-29 | — | — | CN | claimed |
| CN-103435621-A | Spiro quinazoline derivative and preparation method thereof | INST CHEM IND FOREST PROD CAF | 2013-12-11 | — | — | CN | claimed |
| WO-2004014855-A1 | PROCESSES AND POLYMORPHS OF DIARYL-INDOLONE GALR3 ANTAGONISTS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | claimed |
| US-6114540-A | COMBINATORIAL LIBRARIES | ARQULE, INC. (US) | 2000-09-05 | — | — | US | claimed |
| CN-119684105-B | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2026-04-28 | — | — | CN | disclosed |
| CN-119684105-B | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2026-04-28 | — | — | CN | disclosed |
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | disclosed |
| WO-2025037630-A1 | COMPOUND, LIGHT-EMITTING MATERIAL, AND ORGANIC LIGHT-EMITTING ELEMENT | 株式会社Kyulux | 2025-02-20 | — | — | WO | disclosed |
| CN-111423351-B | Chiral copper compound and preparation method and application thereof | 中国科学技术大学 | 2024-03-29 | — | — | CN | disclosed |
| US-4806651-A | Process for preparing 3,3-disubstituted indolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-21 | — | — | US | disclosed |
| EP-0066378-B1 | PHARMACEUTICAL SPIRO-HYDANTOIN DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-02 | — | — | EP | disclosed |
| US-4490381-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS, ALSO ALDOSE REDUCTASE INHIBIIOTRS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-25 | — | — | US | disclosed |
| EP-0028906-B1 | 1'-SUBSTITUTED-SPIRO(IMIDAZOLIDINE-4,3'-INDOLINE)-2,2',5-TRIONES, PROCESSES FOR THEIR MANUFACTURE AND PHARMACEUTICAL COMPOSITIONS THEREOF | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-10-03 | — | — | EP | disclosed |
| US-4386100-A | COMPLICATIONS OF DIABETES OR GALACTOSEMIA | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-05-31 | — | — | US | disclosed |
| EP-0028906-A1 | 1'-Substituted-spiro(imidazolidine-4,3'-indoline)-2,2',5-triones, processes for their manufacture and pharmaceutical compositions thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-05-20 | — | — | EP | disclosed |
| US-4016173-A | Oxindole diamines | CIBA-GEIGY CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |