Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.73 |
| ▸ | BCHE | P06276 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Isatin SCHEMBL1897654 | 0.91 | CES1 (0.83) | CES1BCHENPSR1CES2ALDH1A1 | |
| Phenyl Isatin SCHEMBL916808 | 0.85 | CES1 (1.00) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL8254529 | 0.83 | NR1H3 (0.51) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL14830555 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL30951976 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL2305737 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL14830299 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL29506688 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL20721761 | 0.82 | CES1 (0.73) | CES1BCHENPSR1CES2ALDH1A1 | |
| SCHEMBL5353747 | 0.79 | CES1 (0.64) | CES1BCHENPSR1CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3626699-B1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2023-07-12 | — | — | EP | disclosed |
| US-20210198220-A1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-07-01 | — | — | US | disclosed |
| US-11001563-B2 | SSAO inhibitor | SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) | 2021-05-11 | — | — | US | disclosed |
| US-20200115352-A1 | SSAO INHIBITOR | SHANDONG DANHONG PHARMACEUTICAL CO., LTD. | 2020-04-16 | — | — | US | disclosed |
| EP-3626699-A1 | SSAO INHIBITOR | Shandong Danhong Pharmaceutical Co., Ltd. (CN) | 2020-03-25 | — | — | EP | disclosed |
| CN-104769038-B | Polycarbonate resin composition and molded article | 出光兴产株式会社 | 2017-06-30 | — | — | CN | disclosed |
| CN-105593299-B | Resin composition for optical material, optical film and liquid crystal display device | DIC株式会社 | 2017-03-29 | — | — | CN | disclosed |
| US-7166635-B2 | 3-imino-2-indolones for the treatment of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2007-01-23 | — | — | US | disclosed |
| US-20050148635-A1 | 3-imino-2-indolones for the treatment of depression and/or anxiety | SYNAPTIC PHARMACEUTICAL CORPORATION | 2005-07-07 | — | — | US | disclosed |
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |
| CN-1132216-A | Copolycarbonate, copolycarbonate composition, and method for their manufacture | GEN ELECTRIC (US) | 1996-10-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11001563-B2 | SSAO inhibitor | SSB, ASAH2, AOX1 | CES1 1117/4885BCHE 3796/4885NPSR1 1353/4885 |
| US-20050148635-A1 | 3-imino-2-indolones for the treatment of depression and/or anxiety | GALR3, GALR2, GALR1 | CES1 3556/4885BCHE 3445/4885NPSR1 108/4885 |
| US-20210198220-A1 | SSAO INHIBITOR | SSB, ASAH2, AOX1 | CES1 1117/4885BCHE 3796/4885NPSR1 1353/4885 |
| US-20200115352-A1 | SSAO INHIBITOR | SSB, ASAH2, AOX1 | CES1 1117/4885BCHE 3796/4885NPSR1 1353/4885 |
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | GALR3, GALR2, GALR1 | CES1 3382/4885BCHE 3511/4885NPSR1 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.