Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3468016 | 1.00 | APP (0.52) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL2184521 | 1.00 | APP (0.52) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL9169755 | 1.00 | APP (0.52) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL5527871 | 0.95 | APP (0.57) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL439039 | 0.90 | DGKA (0.50) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL4638212 | 0.87 | APP (0.49) | APPCYP1A2CYP3A4CYP2C8CYP2C9 | |
| SCHEMBL3250259 | 0.87 | GAA (0.49) | GAADGKACNR1CNR2 | |
| SCHEMBL13899816 | 0.86 | GAA (0.53) | GAADGKACNR1CNR2 | |
| SCHEMBL754404 | 0.86 | GAA (0.53) | GAADGKACNR1CNR2 | |
| SCHEMBL208070 | 0.86 | GAA (0.53) | GAADGKACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335262-B1 | Phosphite compounds | YOSHITOMI PHARMACEUTICAL (JP) | 1995-05-31 | — | — | EP | disclosed |
| US-5077424-A | Antioxidants | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0335262-A2 | Phosphite compounds | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |