Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169003 | 0.88 | OXER1 (0.67) | OXER1EGFRKMT2AMEN1KDM4E | |
| SCHEMBL9164659 | 0.85 | OXER1 (0.54) | OXER1ALOX15EGFRKMT2AMEN1 | |
| SCHEMBL9165571 | 0.80 | OXER1 (0.73) | OXER1EGFRKMT2AMEN1KDM4E | |
| SCHEMBL15958718 | 0.78 | OXER1 (0.70) | OXER1KDM4EALDH1A1HSD17B10GAA | |
| SCHEMBL9167173 | 0.77 | OXER1 (0.66) | OXER1EGFRKMT2AMEN1KDM4E | |
| SCHEMBL9166286 | 0.76 | OXER1 (0.74) | OXER1ALOX15EGFRKMT2AMEN1 | |
| SCHEMBL9160699 | 0.76 | OXER1 (0.91) | OXER1EGFRKMT2AMEN1ALDH1A1 | |
| SCHEMBL9160837 | 0.76 | OXER1 (0.91) | OXER1EGFRKMT2AMEN1ALDH1A1 | |
| SCHEMBL9164420 | 0.76 | OXER1 (0.91) | OXER1EGFRKMT2AMEN1ALDH1A1 | |
| SCHEMBL9165525 | 0.76 | OXER1 (0.91) | OXER1EGFRKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |