Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160603 | 1.00 | CNR1 (0.44) | CNR1CNR2OXER1CYP2D6POLB | |
| SCHEMBL9161664 | 1.00 | CNR1 (0.44) | CNR1CNR2OXER1CYP2D6POLB | |
| SCHEMBL9165518 | 0.87 | OXER1 (0.45) | CNR1OXER1POLBMEN1ALDH1A1 | |
| SCHEMBL9163742 | 0.86 | OXER1 (0.44) | CNR1CNR2OXER1POLBMEN1 | |
| SCHEMBL9159829 | 0.86 | OXER1 (0.44) | CNR1CNR2OXER1POLBMEN1 | |
| SCHEMBL9169103 | 0.81 | OXER1 (0.66) | OXER1CYP2D6POLBALDH1A1MAPT | |
| SCHEMBL9164485 | 0.81 | OXER1 (0.66) | OXER1CYP2D6POLBALDH1A1MAPT | |
| SCHEMBL9162650 | 0.76 | OXER1 (0.53) | OXER1CYP2D6POLBMEN1ALDH1A1 | |
| SCHEMBL8959644 | 0.76 | CNR2 (0.58) | CNR1CNR2 | |
| SCHEMBL8960000 | 0.76 | CNR2 (0.58) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |