Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | F7 | P08709 | 4/20 | 0.43 |
| ▸ | F3 | P13726 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9169103 | 1.00 | OXER1 (0.66) | OXER1CYP2D6PPARGPPARAEPHX2 | |
| SCHEMBL9166486 | 0.84 | OXER1 (0.67) | OXER1CYP2D6ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL9161157 | 0.82 | OXER1 (0.65) | OXER1CYP2D6ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL9164420 | 0.82 | OXER1 (0.91) | OXER1ALDH1A1MAPTKMT2AATM | |
| SCHEMBL9165525 | 0.82 | OXER1 (0.91) | OXER1ALDH1A1MAPTKMT2AATM | |
| SCHEMBL9160837 | 0.82 | OXER1 (0.91) | OXER1ALDH1A1MAPTKMT2AATM | |
| SCHEMBL9160699 | 0.82 | OXER1 (0.91) | OXER1ALDH1A1MAPTKMT2AATM | |
| SCHEMBL9161664 | 0.81 | CNR1 (0.44) | OXER1CYP2D6ALDH1A1MAPTPOLB | |
| SCHEMBL9169538 | 0.81 | CNR1 (0.44) | OXER1CYP2D6ALDH1A1MAPTPOLB | |
| SCHEMBL9160603 | 0.81 | CNR1 (0.44) | OXER1CYP2D6ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648208-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994022821-A1 | INDOLE DERIVATIVES AS TESTOSTERONE 5 ALPHA-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |