Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.51 |
| ▸ | AR | P10275 | 6/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.51 |
| ▸ | PGR | P06401 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11594506 | 0.88 | MEN1 (0.79) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL11645440 | 0.84 | MEN1 (0.72) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL11645433 | 0.84 | MEN1 (0.72) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL13558387 | 0.82 | MEN1 (0.70) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL11798369 | 0.82 | MEN1 (0.70) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL8974618 | 0.82 | MEN1 (0.70) | MEN1KMT2ACYP17A1CYP19A1NR3C1 | |
| SCHEMBL6693946 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP19A1NR3C1AR | |
| SCHEMBL6693949 | 0.81 | MEN1 (0.68) | MEN1KMT2ACYP19A1NR3C1AR | |
| SCHEMBL5925193 | 0.81 | PGR (0.70) | MEN1KMT2ACYP19A1NR3C1AR | |
| SCHEMBL149089 | 0.81 | PGR (0.70) | MEN1KMT2ACYP19A1NR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0136465-B1 | Process for the preparation of 17-alpha-acetoxy-1-alpha, 2-alpha-methylene-pregna-4,6-diene-3,20 dione | SCHERING AG (DE) | 1995-05-17 | — | — | EP | disclosed |
| US-3931167-A | Process for the manufacture of 3-keto-6-azido-4,6-bis-dehydro-steroids and intermediates useful therein | SCHERING CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |