Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 11/20 | 1.00 |
| ▸ | THRA | P10827 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | PCNA | P12004 | 2/20 | 0.77 |
| ▸ | PPARG | P37231 | 2/20 | 0.77 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | GABRP | O00591 | 1/20 | 0.77 |
| ▸ | GABRD | O14764 | 1/20 | 0.77 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.77 |
| ▸ | F2 | P00734 | 1/20 | 0.77 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.77 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.77 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.77 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.77 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.77 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619560 | 1.00 | THRB (1.00) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL5545767 | 1.00 | THRB (1.00) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL6827511 | 0.91 | THRB (0.84) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL7277669 | 0.90 | THRB (0.84) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL7277661 | 0.90 | THRB (0.84) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL5549652 | 0.88 | THRB (1.00) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL3219487 | 0.88 | THRB (1.00) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL3219497 | 0.88 | THRB (1.00) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL7276775 | 0.87 | THRB (0.77) | THRBTHRAMEN1KMT2ALMNA | |
| SCHEMBL7276780 | 0.87 | THRB (0.77) | THRBTHRAMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466909-B1 | THYROID HORMONE FOR CARDIAC TREATMENT | BRITISH TECH GROUP USA (US) | 1995-06-28 | — | — | EP | disclosed |